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1¡¢Ò½Ò©¿Æ¼¼¹¤×÷Õß׫дҽҩÂÛÎÄʱһ°ãÒªÇó¸½Ó¢ÎÄÕªÒª£¬Ó¢ÎÄժҪдµÃ׼ȷÓë ·ñ£¬ºÜ´ó³Ì¶ÈÉÏÌåÏÖÁË×÷ÕßµÄѧÊõˮƽ£¬Ò²ÓëÂÛÎĵÄÓ°ÏìÁ¦Óкܴó¹ØÏµ¡£ÎÒÃÇÓÐÐÒ ´Ó¡¶Ò½Ò©µ¼±¨¡·ÔÓÖ¾Éç»ñÈ¡ÁËÏ൱ÊýÁ¿ÂÛÎĵÄÓ¢ÎÄÕªÒªÔ­¸å¡£¸Ã¿¯ÌØÑûÓ¢ÎÄУÒ롪 ¡ªÍ¬»ªÖпƼ¼´óѧͬ¼ÃҽѧԺ·ëÐÂΪ½ÌÊÚ£¬ÄêÓâ¾ÅÑ®ÈÔ·ü°¸±Ê¸û£¬ÎªÕâЩ¸å¼þ×öÁË ´óÁ¿Ï¸ÖÂÉîÈëµÄУÒ빤×÷£¬¿Éν¾ä¾äº¹Ë®×Ö×ÖÖéçá¡£¸øÒ½Ò©¿Æ¼¼ÂÛÎÄÓ¢ÎÄÕªÒªµÄд ×÷ÌṩÁËÒ»¸ö·¶±¾£¬¶Ô¹ã´óÒ½Ò©¿Æ¼¼¹¤×÷ÕßÀ´ËµÒ²ÊÇÒ»´Î¼«ÆäÕä¹óµÄѧϰ»ú»á¡£±¾ ¿¯Ìؼ­Â¼¿¯ÔØÆäÔ­Îļ°·ë½ÌÊÚËù×÷ÐÞÕý¡¢µãÆÀ£¬ÒÔ÷϶ÁÕß¡£ 2¡¢±àÖÆÌåÀý£º±¾Îİ´ÕÕÔ­ÎÄ¡¢ÐÞÕý¡¢µãÆÀ´ÎÐò±àд£»Ð޸ġ¢²åÈë´¦ÒÔºÚÌåбÌå £¬É¾½Ú´¦¸½À¨ºÅ˵Ã÷£¬ÈçÓеãÆÀ¸½ÉϱêÊý×Ö×¢Ã÷¡£ 1¡¢Ô­ÎÄ£º DeterminationofGallicAcidinZhixuetingLiquidsbyTLCScanning ZHOUQun1,XULa-ying2(1.DepartmentofPharmacology,TongjiMedicalC ollege,HuazhongUniversityofScienceandTechnology,Wuhan430030,Ch ina;2.TheFacultyofPharmacy,HubeiCollegeofTraditionalChineseMe dicine,Wuhan430061,China) ABSTRACTObjective:TodeterminethecontentofgallicacidinZhixueti ngliquids.Methods:Zhixuetingliquidsweredissolvedbydistilledwat er,andthenextractedintothesamplewithbutanaletc.Thesampleswe redeterminatedbyTLCscanning(¦ËS=280nm,¦ËR=350nm).Result:Theaver agerecoveryratewas96.36%andRSD=2.39%.Thecontentsofgallicacid in3fivebatchesofsampleswere0.38,0.42and0.47mg/ml.Conclusion: Themethodissimple,convenientandavailable. KEYWORDSTLCScanning;Zhixuetingliquids;Determination;Gallicacid ÐÞÕý£º DeterminationofGallicAcidinChuxueting1oralLiquidsbyTLCScannin g ZHOUQun1,XULa-ying2(1.SchoolofPharmacy2,TongjiMedicalCollege, HuazhongUniversityofScienceandTechnology,Wuhan430030,China;2. TheFacultyofPharmacy,HubeiCollegeofTraditionalChineseMedicine, Wuhan430061,China) AbstractObjective:TodeterminethecontentofgallicacidinChuxueti ngoralLiquids.Methods:TheChuxuetingoralLiquidwasdissolvedind istilledwater,andthenextracted£¨intothesampleɾȥ£©withwater-s aturaledn-butanol3etc.forthepreparationofsamples.Thesampleswe resubjectedtogallicaciddeterminationbyTLCscanning(¦ËS=280nm,¦Ë R=350nm).Results:Theaveragerateofrecoverywas96.36%,£¨andɾȥ£© RSD=2.39%.Thecontentsofgallicacidin3£¨fiveɾȥ£©batchesofsam pleswere0.38,0.42and0.47mg/mlrespectively.Conclusion:Themethod issimple,convenientandfeasible. KEYWORDSTLCScanning;ChuxuetingoralLiquids;Determination;Gallic acid µãÆÀ£º 1¡¢zhixuetingӦΪ¡°Ö¹ÑªÍ£¡±¶ø·Ç¡°³öѪͣ¡±£¬×ÔÏàì¶Ü¡£¡°³öѪͣ¡±Ò²¿ÉÒëΪ hemorrhage-stopping£¬ÒÔ·½±ã¹úÍâ¶ÁÕßÀí½â¡£ 2¡¢school¿É×÷¡°£¨´óѧÀïµÄ£©Ôº¡±½â£¬Ô­ÒâÊÇ¡°Ò©Ñ§Ôº¡±£¬¶ø·Ç¡°Ò©Àí½ÌÑÐÊÒ¡± £¬¹Ê¸ÄÖ®¡£ 3¡¢Ð±Ìån±íʾ¡°Õý¡±¡£2¡¢Ô­ÎÄ£º

ContentDeterminationofEmodininQingreMingmuCapsules

LUOMing-zhu1,ZHANGHong2(1.HubeiProviceInstituteofDrugControl,

Wuhan430030,China;2.The75310MedicalTeamoftheArmy)

ABSTRACTObjectives:TodeterminationcontentofEmodininQingreMingm

uCapsules.Methods:Tlcswasused,silicagelTlcplate,developingso

lventwasBenzene-Ethylfermate-formicacid-Methanol-water(3:1:0.05:0.1

:0.5)ofwhichtheuppersolution¦ËS=435nm,¦ËR=530nm.Result:Thelinea

rrelationshipofsampleapplicationwhichrangedbetween0.168-3.09¦Ìg

wasgood.Theregressionequationwasbelow:Y=105417.7X-1115.6,r=0.9

995;areragerecoverywas100.53%,RSD=3.38%.Conclusion:Thismethodi

ssimple,accurateandconvenient.

KEYWORDSTLcs;QingremingmuCcapsules;Emodin

ÐÞÕý£º

DeterminationofEmodinContentinQingremingmu1Capsules

LUOMing-zhu1,ZHANGHong2(1.HubeiProvicialInstituteofDrugControl

,Wuhan430030,China;2.The75310MedicalTeamoftheArmy)

ABSTRACTObjective:Tosetupamethodforthedetermination£¨contentɾ

È¥£©ofEmodincontentinQingreMingmuCapsules.Methods:IntheTLCa

ssay,a0.5%canboxymethylcellulosesodium(wasusedɾȥ)silicagelG

plateandadevelopingsolventwithamixtureofbenzene¡ªethylformat

e¡ªformicacid¡ªmethanol¡ªwater(3:1:0.05:0.1:0.5)astheuppersolution

wereused.¦ËS=435nm,¦ËR=530nm.Results:Agoodlinearrelationshipwas

foundwhenthesampleamount(whichɾȥ)rangedbetween0.168-3.09¦Ìg

£¨wasgoodɾȥ£©.Theregressionequationwasasfollows:Y=105417.7X-1

115.6,r=0.9995.Theaveragerateofrecoverywas100.53%,RSD=3.38%.Co

nclusion:Themethodissimple,convenientandaccurate.

KEYWORDSTLC;QingreMingmuCcapsules;Emodin

µãÆÀ£º

1¡¢ÖгÉÒ©ÃûÓÃбÌåÊéд£¬Ò²¿ÉÒë×÷removingpathogenicheattoimproveacui

tyofvision¡£



3¡¢Ô­ÎÄ£º

ResearchonTheAcuteToxicityofHuningCapsule

XINZhi-wei,ZANGZhi-he,MAIXiao-xia,FENGJun,YANGWan-qing,LIAOH

ong-li(TeachingandResearchSectionofPharmacy,TheThirdMedicalUn

iversity,ChengduCollegeofPLA610081,China)

ABSTRACTObjective:ToobserveandtesttheacutetoxicityofHuningCa

psuleonKunmingmiceafterani.g.Methods:Countthedeathcasesofm

icein7daysafterthei.g.andworkouttheLD50ofHuningCapsule.R

esults:TheLD50ofHuningCapsuleonmiceis3981mg/kg.

KEYWORDSHuningCapsule;AcuteToxicity;LD50

ÐÞÕý£º

AnExperimentalStudyoftheAcuteToxicityofHuningCapsules1

XINZhi-wei,ZANGZhi-he,MAIXiao-xia,FENGJun,YANGWan-qing,LIAOH

ong-li(TeachingandResearchSectionofPharmacy,ChengduMilitaryMed

icalCollege,TheThirdMilitaryMedicalUniversity,Chengdu610081,Ch

ina)

ABSTRACTObjective:ToobserveanddeterminetheacutetoxicityofHuni

ngcapsules(onKunmingmiceɾȥ)afterasingleintragastricadministr

ationinthemouse.Methods:50Kunmingmicewererandomlydividedinto

5equalgroups,with10animalsineachgroup.Asingledoseof7500,

5630,4200,3150and2360mg/kg-1ofthecontentofthecapsulesweread

ministenedthroughagastrictubetoeachofthemiceofthe5groups,

respectively.Thenumbersofthedeathsofthemicewithin7dayswere

noteddownandthemediarletherdose(LD50)ofHuningCapsuleswascal

culated.(Countthedeathcasesofmicein7daysafterthei.g.andwo

rkouttheLD50ofHuningCapsule.ɾȥ)Results:TheLD50ofHuningCa

psuleinmicewas3981mg/kg.Conclusion:HuningCapsuleshaveonlyami

noracutetoxicity.Itisthereforesafetousethedrugclinically.Fu

rtherstudyofitstoxicityinlong-termapplicationisrequired.

KEYWORDSHuningCapsules;Toxicity,acute;LD50

µãÆÀ£º

1¡¢¡°ºôÄþ½ºÄÒ¡±Ò²¿ÉÒë×÷antitussiveandantiasthmaticcapsules.

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