1¡¢Ò½Ò©¿Æ¼¼¹¤×÷Õß׫дҽҩÂÛÎÄʱһ°ãÒªÇó¸½Ó¢ÎÄÕªÒª£¬Ó¢ÎÄժҪдµÃ׼ȷÓë ·ñ£¬ºÜ´ó³Ì¶ÈÉÏÌåÏÖÁË×÷ÕßµÄѧÊõˮƽ£¬Ò²ÓëÂÛÎĵÄÓ°ÏìÁ¦Óкܴó¹ØÏµ¡£ÎÒÃÇÓÐÐÒ ´Ó¡¶Ò½Ò©µ¼±¨¡·ÔÓÖ¾Éç»ñÈ¡ÁËÏ൱ÊýÁ¿ÂÛÎĵÄÓ¢ÎÄժҪԸ塣¸Ã¿¯ÌØÑûÓ¢ÎÄУÒ롪 ¡ªÍ¬»ªÖпƼ¼´óѧͬ¼ÃҽѧԺ·ëÐÂΪ½ÌÊÚ£¬ÄêÓâ¾ÅÑ®ÈÔ·ü°¸±Ê¸û£¬ÎªÕâЩ¸å¼þ×öÁË ´óÁ¿Ï¸ÖÂÉîÈëµÄУÒ빤×÷£¬¿Éν¾ä¾äº¹Ë®×Ö×ÖÖéçá¡£¸øÒ½Ò©¿Æ¼¼ÂÛÎÄÓ¢ÎÄÕªÒªµÄд ×÷ÌṩÁËÒ»¸ö·¶±¾£¬¶Ô¹ã´óÒ½Ò©¿Æ¼¼¹¤×÷ÕßÀ´ËµÒ²ÊÇÒ»´Î¼«ÆäÕä¹óµÄѧϰ»ú»á¡£±¾ ¿¯Ìؼ¼¿¯ÔØÆäÔÎļ°·ë½ÌÊÚËù×÷ÐÞÕý¡¢µãÆÀ£¬ÒÔ÷϶ÁÕß¡£ 2¡¢±àÖÆÌåÀý£º±¾Îİ´ÕÕÔÎÄ¡¢ÐÞÕý¡¢µãÆÀ´ÎÐò±àд£»Ð޸ġ¢²åÈë´¦ÒÔºÚÌåбÌå £¬É¾½Ú´¦¸½À¨ºÅ˵Ã÷£¬ÈçÓеãÆÀ¸½ÉϱêÊý×Ö×¢Ã÷¡£ 1¡¢ÔÎÄ£º DeterminationofGallicAcidinZhixuetingLiquidsbyTLCScanning ZHOUQun1,XULa-ying2(1.DepartmentofPharmacology,TongjiMedicalC ollege,HuazhongUniversityofScienceandTechnology,Wuhan430030,Ch ina;2.TheFacultyofPharmacy,HubeiCollegeofTraditionalChineseMe dicine,Wuhan430061,China) ABSTRACTObjective:TodeterminethecontentofgallicacidinZhixueti ngliquids.Methods:Zhixuetingliquidsweredissolvedbydistilledwat er,andthenextractedintothesamplewithbutanaletc.Thesampleswe redeterminatedbyTLCscanning(¦ËS=280nm,¦ËR=350nm).Result:Theaver agerecoveryratewas96.36%andRSD=2.39%.Thecontentsofgallicacid in3fivebatchesofsampleswere0.38,0.42and0.47mg/ml.Conclusion: Themethodissimple,convenientandavailable. KEYWORDSTLCScanning;Zhixuetingliquids;Determination;Gallicacid ÐÞÕý£º DeterminationofGallicAcidinChuxueting1oralLiquidsbyTLCScannin g ZHOUQun1,XULa-ying2(1.SchoolofPharmacy2,TongjiMedicalCollege, HuazhongUniversityofScienceandTechnology,Wuhan430030,China;2. TheFacultyofPharmacy,HubeiCollegeofTraditionalChineseMedicine, Wuhan430061,China) AbstractObjective:TodeterminethecontentofgallicacidinChuxueti ngoralLiquids.Methods:TheChuxuetingoralLiquidwasdissolvedind istilledwater,andthenextracted£¨intothesampleɾȥ£©withwater-s aturaledn-butanol3etc.forthepreparationofsamples.Thesampleswe resubjectedtogallicaciddeterminationbyTLCscanning(¦ËS=280nm,¦Ë R=350nm).Results:Theaveragerateofrecoverywas96.36%,£¨andɾȥ£© RSD=2.39%.Thecontentsofgallicacidin3£¨fiveɾȥ£©batchesofsam pleswere0.38,0.42and0.47mg/mlrespectively.Conclusion:Themethod issimple,convenientandfeasible. KEYWORDSTLCScanning;ChuxuetingoralLiquids;Determination;Gallic acid µãÆÀ£º 1¡¢zhixuetingӦΪ¡°Ö¹ÑªÍ£¡±¶ø·Ç¡°³öѪͣ¡±£¬×ÔÏàì¶Ü¡£¡°³öѪͣ¡±Ò²¿ÉÒëΪ hemorrhage-stopping£¬ÒÔ·½±ã¹úÍâ¶ÁÕßÀí½â¡£ 2¡¢school¿É×÷¡°£¨´óѧÀïµÄ£©Ôº¡±½â£¬ÔÒâÊÇ¡°Ò©Ñ§Ôº¡±£¬¶ø·Ç¡°Ò©Àí½ÌÑÐÊÒ¡± £¬¹Ê¸ÄÖ®¡£ 3¡¢Ð±Ìån±íʾ¡°Õý¡±¡£2¡¢ÔÎÄ£º
ContentDeterminationofEmodininQingreMingmuCapsules
LUOMing-zhu1,ZHANGHong2(1.HubeiProviceInstituteofDrugControl,
Wuhan430030,China;2.The75310MedicalTeamoftheArmy)
ABSTRACTObjectives:TodeterminationcontentofEmodininQingreMingm
uCapsules.Methods:Tlcswasused,silicagelTlcplate,developingso
lventwasBenzene-Ethylfermate-formicacid-Methanol-water(3:1:0.05:0.1
:0.5)ofwhichtheuppersolution¦ËS=435nm,¦ËR=530nm.Result:Thelinea
rrelationshipofsampleapplicationwhichrangedbetween0.168-3.09¦Ìg
wasgood.Theregressionequationwasbelow:Y=105417.7X-1115.6,r=0.9
995;areragerecoverywas100.53%,RSD=3.38%.Conclusion:Thismethodi
ssimple,accurateandconvenient.
KEYWORDSTLcs;QingremingmuCcapsules;Emodin
ÐÞÕý£º
DeterminationofEmodinContentinQingremingmu1Capsules
LUOMing-zhu1,ZHANGHong2(1.HubeiProvicialInstituteofDrugControl
,Wuhan430030,China;2.The75310MedicalTeamoftheArmy)
ABSTRACTObjective:Tosetupamethodforthedetermination£¨contentɾ
È¥£©ofEmodincontentinQingreMingmuCapsules.Methods:IntheTLCa
ssay,a0.5%canboxymethylcellulosesodium(wasusedɾȥ)silicagelG
plateandadevelopingsolventwithamixtureofbenzene¡ªethylformat
e¡ªformicacid¡ªmethanol¡ªwater(3:1:0.05:0.1:0.5)astheuppersolution
wereused.¦ËS=435nm,¦ËR=530nm.Results:Agoodlinearrelationshipwas
foundwhenthesampleamount(whichɾȥ)rangedbetween0.168-3.09¦Ìg
£¨wasgoodɾȥ£©.Theregressionequationwasasfollows:Y=105417.7X-1
115.6,r=0.9995.Theaveragerateofrecoverywas100.53%,RSD=3.38%.Co
nclusion:Themethodissimple,convenientandaccurate.
KEYWORDSTLC;QingreMingmuCcapsules;Emodin
µãÆÀ£º
1¡¢ÖгÉÒ©ÃûÓÃбÌåÊéд£¬Ò²¿ÉÒë×÷removingpathogenicheattoimproveacui
tyofvision¡£
3¡¢ÔÎÄ£º
ResearchonTheAcuteToxicityofHuningCapsule
XINZhi-wei,ZANGZhi-he,MAIXiao-xia,FENGJun,YANGWan-qing,LIAOH
ong-li(TeachingandResearchSectionofPharmacy,TheThirdMedicalUn
iversity,ChengduCollegeofPLA610081,China)
ABSTRACTObjective:ToobserveandtesttheacutetoxicityofHuningCa
psuleonKunmingmiceafterani.g.Methods:Countthedeathcasesofm
icein7daysafterthei.g.andworkouttheLD50ofHuningCapsule.R
esults:TheLD50ofHuningCapsuleonmiceis3981mg/kg.
KEYWORDSHuningCapsule;AcuteToxicity;LD50
ÐÞÕý£º
AnExperimentalStudyoftheAcuteToxicityofHuningCapsules1
XINZhi-wei,ZANGZhi-he,MAIXiao-xia,FENGJun,YANGWan-qing,LIAOH
ong-li(TeachingandResearchSectionofPharmacy,ChengduMilitaryMed
icalCollege,TheThirdMilitaryMedicalUniversity,Chengdu610081,Ch
ina)
ABSTRACTObjective:ToobserveanddeterminetheacutetoxicityofHuni
ngcapsules(onKunmingmiceɾȥ)afterasingleintragastricadministr
ationinthemouse.Methods:50Kunmingmicewererandomlydividedinto
5equalgroups,with10animalsineachgroup.Asingledoseof7500,
5630,4200,3150and2360mg/kg-1ofthecontentofthecapsulesweread
ministenedthroughagastrictubetoeachofthemiceofthe5groups,
respectively.Thenumbersofthedeathsofthemicewithin7dayswere
noteddownandthemediarletherdose(LD50)ofHuningCapsuleswascal
culated.(Countthedeathcasesofmicein7daysafterthei.g.andwo
rkouttheLD50ofHuningCapsule.ɾȥ)Results:TheLD50ofHuningCa
psuleinmicewas3981mg/kg.Conclusion:HuningCapsuleshaveonlyami
noracutetoxicity.Itisthereforesafetousethedrugclinically.Fu
rtherstudyofitstoxicityinlong-termapplicationisrequired.
KEYWORDSHuningCapsules;Toxicity,acute;LD50
µãÆÀ£º
1¡¢¡°ºôÄþ½ºÄÒ¡±Ò²¿ÉÒë×÷antitussiveandantiasthmaticcapsules.