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  ¡¡1 Sztriha LK£¬ Sas K£¬ Vecsei L. Aspirin resistance in stroke: 2004. J Neurol Sci. 2005; £¨229-230£©: 163-169.

¡¡¡¡2 Weber ZZ£¬ Zimmermann KC£¬ Meyer-Kirchrath J£¬ et al. Cyclooxygenase-2 in human platelets as a possible factor in aspirin resistance. Lancet. 1999; 353: 900.

¡¡¡¡3 Weber AA£¬ Przytulski B£¬ Schumacher M£¬ et al. Flow cytometry analysis of platelet cyclooxygenase-2 expression: induction of platelet cyclooxygenase-2 in patients under-going coronary artery bypass grafting. Br J Haematol. 2002; 117£¨2£©: 424-426.

¡¡¡¡4 Rocca B£¬ Secchiero P£¬ Ciabattoni G£¬ et al. Cyclooxyge-nase-2 expression is induced during human megakaryo-poiesis and characterizes newly formed platelets. Proc Natl Acad Sci USA. 2002; 99: 7634-7639.

¡¡¡¡5 Kimmel SE£¬ Berlin JA£¬ Reilly M£¬ et al. Patients exposed to rofecoxib and celecoxib have different odds of nonfatal myocardial infarction. Ann Intern Med. 2005; 142£¨3£©: 157-164.

¡¡¡¡6 Johnsen SP£¬ Larsson H£¬ Tarone RE£¬ et al. Risk of hospitalization for myocardial infarction among users of rofecoxib£¬ celecoxib£¬ and other NSAIDs: a population-based case-control study. Arch Intern Med. 2005; 165£¨9£©: 978-984.

¡¡¡¡7 Nurtjahja-Tjendraputra E£¬ Ammit AJ£¬ Roufogalis BD£¬ et al. Effective anti-platelet and COX-1 enzyme inhibi-tors from pungent constituents of ginger. Thromb Res. 2003; 111£¨4-5£©: 259-265.

¡¡¡¡8 Catella-Lawson F£¬ Reilly MP£¬ Kapoor SC£¬ et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. N Engl J Med. 2001; 345£¨25£©: 1809-1817.

¡¡¡¡9 Cryer B£¬ Berlin RG£¬ Cooper SA£¬ et al. Double-blind£¬ randomized£¬ parallel£¬ placebo-controlled study of ibuprofen effects on thromboxane B2 concentrations in aspirin-treated healthy adult volunteers. Clin Ther. 2005; 27£¨2£©: 185-191.

¡¡¡¡10 Kong DF. Aspirin in cardiovascular disorders. What is the optimum dose? Am J Cardiovasc Drugs. 2004; 4£¨3£©: 151-158.

¡¡¡¡11 Helgason CM£¬ Tortorice KL£¬ Winkler SR£¬ et al. Aspi-rin response and failure in cerebral infarction. Stroke. 1993; 24£¨3£©: 345-350.

¡¡¡¡12 Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death£¬ myocardial infarction£¬ and stroke in high risk patients. BMJ. 2002; 324£¨7329£©: 71-86.

¡¡¡¡13 Cox D£¬ Maree AO£¬ Dooley M£¬ et al. Effect of enteric coating on antiplatelet activity of low-dose aspirin inhealthy volunteers. Stroke. 2006; 37£¨8£©: 2153-2158

¡¡¡¡14 Macchi L£¬ Christiaens L£¬ Brabant S£¬ et al. Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate. Thromb Res. 2002; 107£¨1-2£©: 45-49.

¡¡¡¡15 Christiaens L£¬ Macchi L£¬ Herpin D£¬ et al. Resistance to aspirin in vitro at rest and during exercise in patients with angiographically proven coronary artery disease. Thromb Res. 2002; 108£¨2-3£©: 115-119.

¡¡¡¡16 Mattiasson I£¬ Lethagen S£¬ Hillarp A. Increased sensi-tivity to ADP-aggregation in aspirin treated patients with recurrent ischemic stroke? Int Angiol. 2003; 22£¨3£©: 239-242.

¡¡¡¡17 Payne DA£¬ Jones CI£¬ Hayes PD£¬ et al. Platelet inhibi-tion by aspirin is diminished in patients during carotid surgery: a form of transient aspirin resistance? Thromb Haemost. 2004; 92£¨1£©: 89-96.

¡¡¡¡18 Mirkhel A£¬ Peyster E£¬ Sundeen J£¬ et al. Frequency of aspirin resistance in a community hospital. Am J Cardi-ol. 2006; 98£¨5£©: 577-579.

¡¡¡¡19 Macchi L£¬ Christiaens L£¬ Brabant S£¬ et al. Resistance in vitro to low-dose aspirin is associated with platelet PlA1 £¨GP IIIa£© polymorphism but not with C807T £¨GP Ia/IIa£© and C-5T Kozak £¨GP Ibalpha£© polymorphisms. J Am Coll Cardiol. 2003; 42£¨6£©: 1115-1119.

¡¡¡¡20 Gum PA£¬ Kottke-Marchant K£¬ Poggio ED£¬ et al. Profile and prevalence of aspirin resistance in patients with cardiovascular disease. Am J Cardiol. 2001; 88£¨3£©: 230-235.

¡¡¡¡21 Jagroop IA£¬ Mikhailidis DP. Doxazosin£¬ an alpha1- adrenoceptor antagonist£¬ inhibits serotonin-induced shape change in human platelets. J Hum Hypertens. 2001; 15£¨3£©: 203-207.

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