大环内酯类抗生素糖基合成及生物学功能(2)-找论文网

【参考文献】
［1］张部昌. 新酮内酯类抗生素组合生物合成的研究［D］. 北京：军事医学科学院生物工程研究所，2002

［2］张部昌，赵志虎，马清钧. 红霉素生物合成的分子生物学［J］. 生物技术通讯，2001，12(2)：151

［3］张部昌，赵志虎，马清钧. 红霉素基因工程研究进展［J］. 中国生物工程杂志，2002，22(3)：40

［4］ Weissman K J. Polyketelide biosynthesis: understanding and exploiting modularity ［J］. Phlos Transact A Math Phys Eng Sci,2004,362(1825):2671

［5］ Trefzer A, Salas J A, Bechthold A. Genes and enzymes involved in deoxysugar biosynthesis in bacteria ［J］. Nat Prod Rep,1999,16(3):283

［6］ Piepersberg W. Pathway engineering in secondary metaboliteproducing actinomycetes ［J］. Crit Rev Biotechnol,1994,14(3):251

［7］ Amann S, Drager G, Rupprath C, et al. (Chemo) enzymatic synthesis of dTDPactivated 2,6dideoxysugars as building blocks of polyketide antibiotics ［J］. Carbohydr Res,2001,335(1):23

［8］ Melancon C E, Yu W L, Liu H W. TDPmycaminose biosynthetic pathway revised and conversion of desosamine pathway to mycaminose pathway with one gene ［J］. J Am Chem Soc,2005,127(35):12240

［9］ SalahBey K, Doumith M, Michel J M, et al. Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea ［J］. Mol Gen Genet,1998,257(5):542

［10］ Xue Y, Zhao L, Liu H W, et al. A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity ［J］. Proc Natl Acad Sci USA,1998,95(21):12111

［11］ Gaisser S, Reather J, Wirtz G, et al. A defined system for hybrid macrolide biosynthesis in Saccharopolyspora erythraea ［J］. Mol Microbiol,2000,36(2):391

［12］ Melancon C E, Takahashi H, Liu H W. Characterization of tylM3/tylM2 and mydC/mycB pairs required for efficient glycosyltransfer in macrolide antibiotic biosynthesis ［J］. J Am Chem Soc,2004,126(51):16726

［13］ Lee H Y, Chung H S, Hang C, et al. Reconstitution and characterizationof a new desosaminyl transferase EryCIII from the erythromycin biosynthetic pathway ［J］. J Am Chem Soc,2004,126(32):9924

［14］ Mulichak A M, Losey H C, Walsh C T, et al. Structure of the UDPglucosyltransferase GtfB that modifies the heptapeptideaglycone in the biosynthesis of vancomycin group antibiotics ［J］. Structure,2001,9(7):547

［15］ Floss H G. Antibiotic biosynthesis: from natural to unnatural compounds ［J］. J Ind Microbiol Biotechnol,2001,27(3):183

［16］ Schlunzen F, Zarivach R, Harms J, et al. Structural basis for the interaction of antibiotics with the peptidyltransferase center in eubacteria ［J］. Nature,2001,413(6858):814

［17］ Fish S A, Cundliffe E. Structureactivity studies of tylosinrelated macrolides ［J］. J Antibiot,1996,49(10):1044

［18］ Poulsen S M, Kofoed C, Vester B. Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin ［J］. J Mol Biol,2000,304(3):471

［19］ RodriguezFonseca C, Phan H, Long K S, et al. PuromycinrRNA interaction sites at the peptidyl transferase center ［J］. RNA,2000,6(5):744

［20］ Fish S A, Cundliffe E. Stimulation of polyketidemetabolism in Streptomyces fradiae by tylosin and its glycosylated precursors ［J］. Microbiology,1997,143(12):3871

［21］ Butler A R, Flint S A, Cundliffe E. Feedback control of polyketide metabolism during tylosin production ［J］. Microbiology,2001,147(4):795

［22］ Waldron C, Matsushima P, Rosteck P R, et al. Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa ［J］. Chem Biol,2001,8(5):487

［23］ Jenkins G, Cundliffe E. Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics ［J］. Gene,1991,108(1):55

［24］ Zhao L, Beyer N J, Borisova S A, et al. Betaglucosylation as a part of selfresistance mechanism in methymycin/pikromycin producing strain Streptomyces venezuele ［J］. Biochemistry,2003,42(50):14794

［25］ Sasaki J, Mizoue K, Morimoto S, et al. Microbial glycosylation of macrolide antibiotics by Streptomyces hygroscopicus ATCC 31080 and distribution of a macrolide glycosyltransferase in several Streptomyces strains ［J］. J Antibiot (Tokyo),1996,49(11):1110

［26］ Vilches C, Hernandez C, Mendez C, et al. Role of glycosylation and deglycosylation in biosynthesis of and resistance to oleandomycin in the producer organism, Streptomyces antibioticus ［J］. J Bacteriol,1992,174(1):161

［27］ Zhao L, Ahlert J, Xue Y, et al. Engineering a methymycin/pikromycincalicheamicin hybrid: construciton of two new macrolides carrying a designed sugar moiety ［J］. J Am Chem Soc,1999,121(6):9881

［28］ Gaisser S, Lill R, Wirtz G, et al. New erythromycin derivatives from Saccharopolyspora erythraea using sugar Omethyltransferases from the spinosyn biosynthetic gene cluster ［J］. Mol Microbiol,2001,41(5):1223

［29］ Borisova S A, Zhao L, Sheman D H, et al. Biosynthesis of desosamine: construction of a new macrolide carrying a genetically designed sugar moiety ［J］. Org Lett,1999,15(1):133

［30］ Zhao L, Borisova S A, Yeung S M, et al. Study of C4 deoxygenation in the biosynthesis of desosamine: evidence implicating a novel mechanism ［J］. J Am Chem Soc,2001,123(32):7909

［31］ SalahBey K, Doumith M, Michel J M, et al. Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea ［J］. Mol Gen Genet,1998,275(5):542

［32］ Summers R G, Donadio S, Staver M J, et al. Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in Lmycarose and Ddesosamine production ［J］. Microbiology,1997,143(10):3251

［33］ Doumith M, Legrand R, Lang C, et al. Interspecies complementation in Saccharopolyspora erythraea: elucidation of the function of oleP1, oleG1 and oleG2 from the oleandomycin biosynthetic gene cluster of Streptomyces antibioticus and generation of new erythromycin derivatives ［J］. Mol Microbiol,1999,34(5):1039

［34］ AguirrezabalagaI, Olano C, Allende N, et al. Identification and expression of genes involved in biosynthesis of LOleandrose and its intermediate LOlivose in the oleandomycin producer Streptomyces antibioticus ［J］. Antimicrob Agents Chemother,2000,44(5):1266

［35］ Gaisser S, Reather J, Wirtz G, et al. A defined system for hybrid macrolide biosynthesis in Saccharopolyspora erythraea ［J］. Mol Microbiol,2000,36(2):391

［36］ Ward S L, Hu Z, Schirmer A, et al. Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae ［J］. Antimicrob Agents Chemother,2004,48(12):4703

［37］ Tang L, McDaniel R. Construction of desosamine containing polyketide libraries using a glycosyltransferase with broad substrate specificity ［J］. Chem Biol,2001,8(6):547

［38］ Hong J S, Park S H, Choi C Y, et al. New olivosyl derivatives of methymycin/pikromycin from an engineered strain of Streptomyces venezuelae ［J］. FEMS Microbiol Lett,2004,238(2):391

［39］ Jung W S, Lee S K, Hong J S, et al. Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae ［J］. Appl Microbiol Biotechnol,2006,72(4):763

［40］ Allen N E. Mcrolide resistance in Staphylococcus aureus: inducers of macrolide resistance ［J］. Antimicrob Agents Chemother,1977,11(4):669

［41］ Xue Q, Ashley G, Hutchinson C R, et al. A multiplasmid approach to preparing large libraries of polyketides ［J］. Proc Natl Acad Sci USA,1999,96(21):11740

［42］ McDaniel R, Thamchaipenet A, Gustafsson C, et al. Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel′unnatural′ natural products ［J］. Proc Natl Acad Sci USA,1999,96(5):1846

［43］张部昌，赵志虎，王以光，等. 合成酮内酯类3脱氧3羰基红霉内酯B糖多孢红霉菌M的构建［J］. 生物工程学报，2002，18(1)：198

［44］李凌凌，张部昌. 糖多孢红霉菌λ30SRR突变体构建及产物鉴定［J］. 军事医学科学院院刊，2004，28(4)：314

［45］曹孟婵，张部昌，马清钧. 糖多孢红霉菌A226YA突变体构建及产物分析［J］. 军事医学科学院院刊，2006，30(5)：428

［46］ Gokhale R S, Tsuji S Y, Cane D E, et al. Dissecting and exploiting intermodular communication in polyketide synthases ［J］. Science,1999,284(5413):482

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